4 22126238Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity0Meta AI6Microsoft · Copilot0Amazon2Apple3Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 648 African American or Afro-Caribbean cases, 119,584 African American or Afro-Caribbean controls, 3,891 European ancestry cases, 439,202 European ancestry controls, 409 Hispanic or Latin American cases, 58,515 Hispanic or Latin American controls.
The effect
Each copy of the A allele shifted the measure 1.83 lower (95% confidence interval 1.76-1.89); p = 3 × 10−11.
How common The A allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 11, band 11p12 — in an intron of LRRC4C.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronic fatigue syndrome (PheCode 798.1) compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronic fatigue syndrome (PheCode 798.1).
G/GPublished research associates this genotype with typical/baseline likelihood of Chronic fatigue syndrome (PheCode 798.1) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs189511601
What is rs189511601?
rs189511601 is a single position in the genome, in or near the LRRC4C gene. Published research associates it with chronic fatigue syndrome (phecode 798.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs189511601 linked to?
On MyGeneLog this position is linked to Chronic Fatigue Syndrome (ME/CFS). The research behind each link, and its sources, are set out on that condition page.
Does having rs189511601 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs189511601 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 22126238Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity0Meta AI6Microsoft · Copilot0Amazon2Apple3Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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