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Who was studied 2,254 Han Chinese ancestry cases, 3,001 Han Chinese ancestry controls; replicated in 8,226 Han Chinese ancestry cases, 7,578 Han Chinese ancestry controls.
The effect
Each copy of the G allele carried 1.27 times the odds of Polycystic ovary syndrome; p = 1 × 10−22.
How common The G allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 11, band 11q22.1 — in an intron of YAP1.
What each result means
A/ANo copy of the version the research linked to Polycystic ovary syndrome. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Polycystic ovary syndrome. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Polycystic ovary syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1894116 is a single position in the genome, in or near the YAP1 gene. Published research associates it with polycystic ovary syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1894116 linked to?
On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs1894116 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1894116 come from?
GWAS Catalog, Nat Genet 2012, PMID:22885925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 392225222121Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others21Total39Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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