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Cognitive performance

SCMH1-DT · rs1892419

Where this position leads

Condition: Educational Attainment

rs1892419 Condition: Educational Attainment Educational Attainment Condition rs1892419 rs1892419 SCMH1-DT

What the study found

Who was studied 257,841 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0276 higher (95% confidence interval 0.021-0.034); p = 3 × 10−16.

How common The T allele had a frequency of about 77% in the people studied.

Where it sits Chromosome 1, band 1p34.2 — in an intron of SCMH1-DT.

What each result means

C/C No copy of the version the research linked to Cognitive performance. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cognitive performance. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cognitive performance. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1892419

What is rs1892419?

rs1892419 is a single position in the genome, in or near the SCMH1-DT gene. Published research associates it with cognitive performance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1892419 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs1892419 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1892419 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cognitive performance (rs1892419). MyGeneLog™. https://www.mygenelog.com/variants/rs1892419

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