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Polyunsaturated fatty acid levels

FER1L4 · rs188878

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10−20.

Where it sits Chromosome 20, band 20q11.22 — in an intron of FER1L4.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Polyunsaturated fatty acid levels — no copies of the reported risk allele.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Polyunsaturated fatty acid levels.
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Polyunsaturated fatty acid levels compared to the general population.
Source

Questions about rs188878

What is rs188878?

rs188878 is a single position in the genome, in or near the FER1L4 gene. Published research associates it with polyunsaturated fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs188878 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs188878 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Polyunsaturated fatty acid levels (rs188878). MyGeneLog™. https://www.mygenelog.com/variants/rs188878

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