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Red blood cell count

RREB1 · rs188762161

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0682 higher (95% confidence interval 0.053-0.084); p = 7 × 10−18.

How common The C allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 6, band 6p24.3 — in an intron of RREB1.

What each result means

C/C Two copies of the version the research linked to Red blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Red blood cell count. That is a smaller link than two copies.
G/G No copy of the version the research linked to Red blood cell count. This is the starting point the study compared everyone against.
Source

Questions about rs188762161

What is rs188762161?

rs188762161 is a single position in the genome, in or near the RREB1 gene. Published research associates it with red blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs188762161 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs188762161 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Red blood cell count (rs188762161). MyGeneLog™. https://www.mygenelog.com/variants/rs188762161

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