Sensitive

Inflammatory bowel disease (Tractor method with European ancestry)

HLA-DMB · rs188746689

Where this position leads

Condition: Inflammatory Bowel Disease

rs188746689 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs188746689 rs188746689 HLA-DMB

What the study found

Who was studied up to 1,627 Hispanic cases, up to 5,042 Hispanic controls.

The effect Each copy of the G allele carried 3.98 times the odds of Inflammatory bowel disease (Tractor method with European ancestry) (95% confidence interval 2.637973205-6.003658919); p = 5 × 10−11.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of HLA-DMB.

What each result means

A/A No copy of the version the research linked to Inflammatory bowel disease (Tractor method with European ancestry). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Inflammatory bowel disease (Tractor method with European ancestry). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Inflammatory bowel disease (Tractor method with European ancestry). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs188746689

What is rs188746689?

rs188746689 is a single position in the genome, in or near the HLA-DMB gene. Published research associates it with inflammatory bowel disease (tractor method with european ancestry). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs188746689 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs188746689 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs188746689 come from?

GWAS Catalog, Gastroenterology 2026, PMID:41661118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Inflammatory bowel disease (Tractor method with European ancestry) (rs188746689). MyGeneLog™. https://www.mygenelog.com/variants/rs188746689

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