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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 8,186 Finnish ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.49 SD units lower (95% confidence interval 0.35-0.63); p = 3 × 10−12.
Where it sits Chromosome 18, band 18q12.1 — between genes, 93 kb from PA2G4P3.
What each result means
A/ANo copy of the version the research linked to TRAIL levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to TRAIL levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to TRAIL levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2017 · PMID 27989323
Questions about rs188740444
What is rs188740444?
rs188740444 is a single position in the genome, in or near the near PA2G4P3 gene. Published research associates it with trail levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs188740444 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs188740444 come from?
GWAS Catalog, American journal of human genetics 2017, PMID:27989323. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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