Sensitive

Alzheimer disease and age of onset

near LINC01605 · rs188420713

What the study found

Who was studied 2,478 European ancestry cases, 979 ancestry controls both from the same 1,070 families.

The effect Each copy of the T allele shifted the measure 6.33 higher; p = 2 × 10−10.

Where it sits Chromosome 8, band 8p11.23 — between genes, 129.7 kb from LINC01605.

What each result means

C/C No copy of the version the research linked to Alzheimer disease and age of onset. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alzheimer disease and age of onset. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alzheimer disease and age of onset. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs188420713

What is rs188420713?

rs188420713 is a single position in the genome, in or near the near LINC01605 gene. Published research associates it with alzheimer disease and age of onset. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs188420713 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs188420713 come from?

GWAS Catalog, Molecular psychiatry 2016, PMID:26830138. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer disease and age of onset (rs188420713). MyGeneLog™. https://www.mygenelog.com/variants/rs188420713

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