Mean platelet thrombocyte volume (UKB data field 30100)
near DSTYK · rs188249176
0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0995 lower (95% confidence interval 0.071-0.128); p = 1 × 10−12.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — between genes, 2.1 kb from DSTYK.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Mean platelet thrombocyte volume (UKB data field 30100) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean platelet thrombocyte volume (UKB data field 30100).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean platelet thrombocyte volume (UKB data field 30100) compared to the general population.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs188249176
What is rs188249176?
rs188249176 is a single position in the genome, in or near the near DSTYK gene. Published research associates it with mean platelet thrombocyte volume (ukb data field 30100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs188249176 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs188249176 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs188249176 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Mean platelet thrombocyte volume (UKB data field 30100) (rs188249176). MyGeneLog™. https://www.mygenelog.com/variants/rs188249176