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Who was studied 293,723 European ancestry individuals with educational attainment, 9,130 European ancestry AUD cases, 112,474 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 6 × 10−11.
Where it sits Chromosome 17, band 17q21.31 — a synonymous change in PLEKHM1.
What each result means
C/CNo copy of the version the research linked to Education attainment or alcohol use disorders. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Education attainment or alcohol use disorders. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Education attainment or alcohol use disorders. That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in psychiatry · 2023 · PMID 38250258 · open access
Questions about rs1879581
What is rs1879581?
rs1879581 is a single position in the genome, in or near the PLEKHM1 gene. Published research associates it with education attainment or alcohol use disorders. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1879581 linked to?
On MyGeneLog this position is linked to Alcohol Use Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs1879581 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1879581 come from?
GWAS Catalog, Frontiers in psychiatry 2023, PMID:38250258. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Education attainment or alcohol use disorders (rs1879581). MyGeneLog™. https://www.mygenelog.com/variants/rs1879581