Standard

Coffee consumption (cups per day)

ADD1 · rs1877723

What the study found

Who was studied 227,666 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.04 cups per day lower; p = 3 × 10−10.

How common The T allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 4, band 4p16.3 — in an intron of ADD1.

What each result means

C/C No copy of the version the research linked to Coffee consumption (cups per day). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coffee consumption (cups per day). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coffee consumption (cups per day). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1877723

What is rs1877723?

rs1877723 is a single position in the genome, in or near the ADD1 gene. Published research associates it with coffee consumption (cups per day). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1877723 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1877723 come from?

GWAS Catalog, American journal of kidney diseases : the official journal of the National Kidney Foundation 2020, PMID:31837886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coffee consumption (cups per day) (rs1877723). MyGeneLog™. https://www.mygenelog.com/variants/rs1877723

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