Standard

CFHR2 protein levels

near CFHR4 · rs187717871

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.562 lower (95% confidence interval 0.52-0.61); p = 2 × 10−198.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q31.3 — between genes, 7.6 kb from CFHR4.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of CFHR2 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with CFHR2 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of CFHR2 protein levels — no copies of the reported risk allele.
Source

Questions about rs187717871

What is rs187717871?

rs187717871 is a single position in the genome, in or near the near CFHR4 gene. Published research associates it with cfhr2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs187717871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs187717871 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CFHR2 protein levels (rs187717871). MyGeneLog™. https://www.mygenelog.com/variants/rs187717871

← See all variants