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Who was studied 278 Spanish ancestry cases, 1,517 Spanish ancestry controls; replicated in up to 130 Spanish ancestry cases, up to 605 Spanish ancestry controls.
The effect
Each copy of the A allele carried 1.61 times the odds of Behcet's disease (95% confidence interval 1.36-1.89); p = 2 × 10−8.
How common The A allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 3, band 3q25.33 — in an intron of IL12A-AS1.
What each result means
A/ATwo copies of the version the research linked to Behcet's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Behcet's disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Behcet's disease. This is the starting point the study compared everyone against.
rs1874886 is a single position in the genome, in or near the IL12A gene. Published research associates it with behcet's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1874886 linked to?
On MyGeneLog this position is linked to Behcet's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1874886 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1874886 come from?
GWAS Catalog, PloS one 2016, PMID:27548383. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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