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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 133,441 Hispanic or Latin American individuals, 391,811 European ancestry individuals.
The effect
Each copy of the T allele carried 3.59 times the odds of Clonal hematopoiesis (TET2 mutation) (95% confidence interval 2.81-4.6); p = 4 × 10−18.
Where it sits Chromosome 14, band 14q32.13 — in an intron of LINC02318.
What each result means
C/CNo copy of the version the research linked to Clonal hematopoiesis (TET2 mutation). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Clonal hematopoiesis (TET2 mutation). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Clonal hematopoiesis (TET2 mutation). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 39948438 · open access
Questions about rs187319135
What is rs187319135?
rs187319135 is a single position in the genome, in or near the near GLRX5 gene. Published research associates it with clonal hematopoiesis (tet2 mutation). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs187319135 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs187319135 come from?
GWAS Catalog, Nature genetics 2025, PMID:39948438. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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