Standard

Urate levels

ZNF160 · rs187171029

Where this position leads

Condition: Gout

rs187171029 Condition: Gout Gout Condition rs187171029 rs187171029 ZNF160

What the study found

Who was studied 2077 British ancestry individuals from 6863 families..

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−8.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 19, band 19q13.41 — in an intron of ZNF160.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Urate levels — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urate levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urate levels compared to the general population.
Source

Questions about rs187171029

What is rs187171029?

rs187171029 is a single position in the genome, in or near the ZNF160 gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs187171029 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs187171029 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs187171029 come from?

GWAS Catalog, Genome Med 2017, PMID:28270201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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