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Blood protein levels

BCAM · rs186872766

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 3,200 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 1.02 lower (95% confidence interval 0.74-1.3); p = 1 × 10⁻¹².

How common The G allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 19, band 19q13.32 — in an intron of CBLC.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Blood protein levels — no copies of the reported risk allele.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Blood protein levels.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Blood protein levels compared to the general population.

Source

Co-regulatory networks of human serum proteins link genetics to disease

Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Horman SR, Aspelund T, Shu L

and 17 more — show all

Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V

Science (New York, N.Y.) · 2018 · PMID 30072576

Questions about rs186872766

What is rs186872766?

rs186872766 is a single position in the genome, in or near the BCAM gene. Published research associates it with blood protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs186872766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs186872766 come from?

GWAS Catalog, Science (New York, N.Y.) 2018, PMID:30072576. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Blood protein levels (rs186872766). MyGeneLog™. https://www.mygenelog.com/variants/rs186872766

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