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STAB2 protein levels

LINC02401 · rs186824649

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.406 lower (95% confidence interval 0.34-0.47); p = 1 × 10−38.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 12, band 12q23.3 — in an intron of LINC02401.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of STAB2 protein levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with STAB2 protein levels.
G/G Published research associates this genotype with typical/baseline likelihood of STAB2 protein levels — no copies of the reported risk allele.
Source

Questions about rs186824649

What is rs186824649?

rs186824649 is a single position in the genome, in or near the LINC02401 gene. Published research associates it with stab2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs186824649 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs186824649 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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STAB2 protein levels (rs186824649). MyGeneLog™. https://www.mygenelog.com/variants/rs186824649

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