Standard
Lung function (FEV1)
LOC644172 · rs186806998
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Lung function (FEV1) — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lung function (FEV1).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lung function (FEV1) compared to the general population.
Source
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Wyss AB,
Sofer T,
Lee MK,
Terzikhan N,
Nguyen JN,
Lahousse L,
Latourelle JC,
Smith AV,
Bartz TM,
Feitosa MF,
Gao W,
Ahluwalia TS
and 91 more — show all
Tang W,
Oldmeadow C,
Duan Q,
de Jong K,
Wojczynski MK,
Wang XQ,
Noordam R,
Hartwig FP,
Jackson VE,
Wang T,
Obeidat M,
Hobbs BD,
Huan T,
Gui H,
Parker MM,
Hu D,
Mogil LS,
Kichaev G,
Jin J,
Graff M,
Harris TB,
Kalhan R,
Heckbert SR,
Paternoster L,
Burkart KM,
Liu Y,
Holliday EG,
Wilson JG,
Vonk JM,
Sanders JL,
Barr RG,
de Mutsert R,
Menezes AMB,
Adams HHH,
van den Berge M,
Joehanes R,
Levin AM,
Liberto J,
Launer LJ,
Morrison AC,
Sitlani CM,
Celedón JC,
Kritchevsky SB,
Scott RJ,
Christensen K,
Rotter JI,
Bonten TN,
Wehrmeister FC,
Bossé Y,
Xiao S,
Oh S,
Franceschini N,
Brody JA,
Kaplan RC,
Lohman K,
McEvoy M,
Province MA,
Rosendaal FR,
Taylor KD,
Nickle DC,
Williams LK,
Burchard EG,
Wheeler HE,
Wheeler HE,
Sin DD,
Gudnason V,
North KE,
Fornage M,
Psaty BM,
Myers RH,
O'Connor G,
Hansen T,
Laurie CC,
Cassano PA,
Sung J,
Kim WJ,
Attia JR,
Lange L,
Boezen HM,
Thyagarajan B,
Rich SS,
Mook-Kanamori DO,
Horta BL,
Uitterlinden AG,
Im HK,
Cho MH,
Brusselle GG,
Gharib SA,
Dupuis J,
Manichaikul A,
London SJ
Nature communications · 2018 · PMID 30061609 · open access
Questions about rs186806998
What is rs186806998?
rs186806998 is a single position in the genome, in or near the LOC644172 gene. Published research associates it with lung function (fev1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs186806998 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs186806998 come from?
GWAS Catalog, Nat Commun 2018, PMID:30061609. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants