0 211422228Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others8Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 48,843 European ancestry cases, 1,190,837 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 5 × 10−13.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 15, band 15q22.31 — in an intron of SMAD6.
What each result means
A/ATwo copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35332129 · open access
Questions about rs1866745
What is rs1866745?
rs1866745 is a single position in the genome, in or near the SMAD6 gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1866745 linked to?
On MyGeneLog this position is linked to Carpal Tunnel Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs1866745 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1866745 come from?
GWAS Catalog, Nature communications 2022, PMID:35332129. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 211422228Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others8Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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