Standard

Mean platelet volume

CD226 · rs1865761

Where this position leads

Condition: Blood Cell Counts

rs1865761 Condition: Blood Cell Counts Blood Cell Counts Condition rs1865761 rs1865761 CD226

What the study found

Who was studied 164,454 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0832 higher (95% confidence interval 0.076-0.09); p = 4 × 10−117.

How common The C allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 18, band 18q22.2 — in an intron of CD226.

What each result means

C/C Two copies of the version the research linked to Mean platelet volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet volume. This is the starting point the study compared everyone against.
Source

Questions about rs1865761

What is rs1865761?

rs1865761 is a single position in the genome, in or near the CD226 gene. Published research associates it with mean platelet volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1865761 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs1865761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1865761 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean platelet volume (rs1865761). MyGeneLog™. https://www.mygenelog.com/variants/rs1865761

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