C8orf34 · rs1865442
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 91,100 European ancestry cases, 258,900 European ancestry controls; replicated in 28,284 European ancestry cases, 75,578 European ancestry controls, 2,520 South Asian ancestry cases, 4,639 South Asian ancestry controls, 2,414 African ancestry cases, 4,845 African ancestry controls, 401 Chinese ancestry cases, 1,084 Chinese ancestry controls.
The effect Each copy of the C allele shifted the measure 0.052 lower (95% confidence interval 0.038-0.066); p = 2 × 10−13.
How common The C allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 8, band 8q13.2 — in an intron of C8orf34.
rs1865442 is a single position in the genome, in or near the C8orf34 gene. Published research associates it with back pain. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Pain 2019, PMID:30747904. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Back pain (rs1865442). MyGeneLog™. https://www.mygenelog.com/variants/rs1865442