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Who was studied 12,312 European ancestry cases, 389,344 European ancestry controls.
The effect
Each copy of the T allele carried 1.12 times the odds of Carpal tunnel syndrome (95% confidence interval 1.08–1.15); p = 5 × 10−13.
How common The T allele had a frequency of about 76% in the people studied.
Where it sits Chromosome 2, band 2q35 — in an intron of TESHL.
What each result means
A/ANo copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 30833571 · open access
Questions about rs1863190
What is rs1863190?
rs1863190 is a single position in the genome, in or near the DIRC3 gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1863190 linked to?
On MyGeneLog this position is linked to Carpal Tunnel Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs1863190 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1863190 come from?
GWAS Catalog, Nature communications 2019, PMID:30833571. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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