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Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.267 lower (95% confidence interval 0.24-0.3); p = 5 × 10−81.
How common The C allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 9, band 9p24.1 — between genes, 13.6 kb from SELENOTP1.
What each result means
C/CTwo copies of the version the research linked to Eosinophill percentage (UKB data field 30210). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Eosinophill percentage (UKB data field 30210). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Eosinophill percentage (UKB data field 30210). This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs186174039
What is rs186174039?
rs186174039 is a single position in the genome, in or near the near SELENOTP1 gene. Published research associates it with eosinophill percentage (ukb data field 30210). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs186174039 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs186174039 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs186174039 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Eosinophill percentage (UKB data field 30210) (rs186174039). MyGeneLog™. https://www.mygenelog.com/variants/rs186174039