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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,045 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.969 lower (95% confidence interval 0.75-1.18); p = 8 × 10−19.
Where it sits Chromosome 17, band 17p13.2 — between genes, 4.2 kb from ALOX15.
What each result means
A/ATwo copies of the version the research linked to Sphingomyelin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sphingomyelin levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sphingomyelin levels. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31551469 · open access
Questions about rs185900616
What is rs185900616?
rs185900616 is a single position in the genome, in or near the GLTPD2 gene. Published research associates it with sphingomyelin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs185900616 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs185900616 come from?
GWAS Catalog, Nature communications 2019, PMID:31551469. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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