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Who was studied 1,930 European ancestry cases, 13,634 European ancestry controls.
The effect
Each copy of the T allele carried 6.37 times the odds of Eosinophilic esophagitis (95% confidence interval 3.38-11.97); p = 1 × 10−8.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 10, band 10q21.1 — in a non-coding transcript of PRKG1.
What each result means
A/ANo copy of the version the research linked to Eosinophilic esophagitis. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Eosinophilic esophagitis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Eosinophilic esophagitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of allergy and clinical immunology · 2022 · PMID 34506852
Questions about rs185811602
What is rs185811602?
rs185811602 is a single position in the genome, in or near the PRKG1 gene. Published research associates it with eosinophilic esophagitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs185811602 linked to?
On MyGeneLog this position is linked to Eosinophilic Esophagitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs185811602 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs185811602 come from?
GWAS Catalog, The Journal of allergy and clinical immunology 2022, PMID:34506852. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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