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Subarachnoid hemorrhage (PheCode 430.1)

near U3 · rs185673589

What the study found

Who was studied 228 African American or Afro-Caribbean cases, 121,537 African American or Afro-Caribbean controls, 737 European ancestry cases, 449,997 European ancestry controls.

The effect Each copy of the G allele shifted the measure 2.33 lower (95% confidence interval 2.28-2.38); p = 4 × 10−11.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 6, band 6q15 — between genes, 96.8 kb from U3.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Subarachnoid hemorrhage (PheCode 430.1) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Subarachnoid hemorrhage (PheCode 430.1).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Subarachnoid hemorrhage (PheCode 430.1) compared to the general population.
Source

Questions about rs185673589

What is rs185673589?

rs185673589 is a single position in the genome, in or near the near U3 gene. Published research associates it with subarachnoid hemorrhage (phecode 430.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs185673589 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs185673589 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Subarachnoid hemorrhage (PheCode 430.1) (rs185673589). MyGeneLog™. https://www.mygenelog.com/variants/rs185673589

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