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C-reactive protein levels

AK4 · rs1855981

Where this position leads

Condition: C-Reactive Protein Levels

rs1855981 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs1855981 rs1855981 AK4

What the study found

Who was studied 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0159 lower (95% confidence interval 0.011-0.021); p = 2 × 10−9.

Where it sits Chromosome 1, band 1p31.3 — in the 3′ untranslated region of AK4.

What each result means

C/C Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs1855981

What is rs1855981?

rs1855981 is a single position in the genome, in or near the AK4 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1855981 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs1855981 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1855981 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels (rs1855981). MyGeneLog™. https://www.mygenelog.com/variants/rs1855981

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