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Hair colour (natural, before greying): Red (UKB data field 1747_2)

FANCA · rs185525869

What the study found

Who was studied 20,692 European ancestry cases, 434,472 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.87 lower (95% confidence interval 0.69-1.05); p = 4 × 10−20.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 16, band 16q24.3 — in an intron of FANCA.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hair colour (natural, before greying): Red (UKB data field 1747_2) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hair colour (natural, before greying): Red (UKB data field 1747_2).
G/G Published research associates this genotype with typical/baseline likelihood of Hair colour (natural, before greying): Red (UKB data field 1747_2) — no copies of the reported risk allele.
Source

Questions about rs185525869

What is rs185525869?

rs185525869 is a single position in the genome, in or near the FANCA gene. Published research associates it with hair colour (natural, before greying): red (ukb data field 1747_2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs185525869 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs185525869 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hair colour (natural, before greying): Red (UKB data field 1747_2) (rs185525869). MyGeneLog™. https://www.mygenelog.com/variants/rs185525869

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