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Coronary artery disease

MRAS · rs185244

Where this position leads

Condition: Coronary Artery Disease

rs185244 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs185244 rs185244 MRAS

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Coronary artery disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary artery disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary artery disease compared to the general population.
Source
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
van der Harst P, Verweij N
Circulation research · 2018 · PMID 29212778 · open access

Questions about rs185244

What is rs185244?

rs185244 is a single position in the genome, in or near the MRAS gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs185244 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs185244 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs185244 come from?

GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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