0 6123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 612 African American or Afro-Caribbean cases, 54,893 African American or Afro-Caribbean controls, 4,609 European ancestry cases, 311,059 European ancestry controls, 454 Hispanic or Latin American cases, 28,860 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 2.1 lower (95% confidence interval 2.04-2.15); p = 1 × 10−11.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 13, band 13q12.12 — in an intron of SACS.
What each result means
A/ANo copy of the version the research linked to Biological Mother: Bipolar Disorder. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Biological Mother: Bipolar Disorder. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Biological Mother: Bipolar Disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs185219225
What is rs185219225?
rs185219225 is a single position in the genome, in or near the SACS gene. Published research associates it with biological mother: bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs185219225 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs185219225 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs185219225 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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