Standard
Sum eosinophil basophil counts
FNIP1 · rs185120612
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 171,771 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.329 higher (95% confidence interval 0.23-0.43); p = 3 × 10−10.
How common The A allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 5, band 5q31.1 — in an intron of FNIP1.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sum eosinophil basophil counts compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sum eosinophil basophil counts.
G/G
Published research associates this genotype with typical/baseline likelihood of Sum eosinophil basophil counts — no copies of the reported risk allele.
Source
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
Astle WJ,
Elding H,
Jiang T,
Allen D,
Ruklisa D,
Mann AL,
Mead D,
Bouman H,
Riveros-Mckay F,
Kostadima MA,
Lambourne JJ,
Sivapalaratnam S
and 62 more — show all
Downes K,
Kundu K,
Bomba L,
Berentsen K,
Bradley JR,
Daugherty LC,
Delaneau O,
Freson K,
Garner SF,
Grassi L,
Guerrero J,
Haimel M,
Janssen-Megens EM,
Kaan A,
Kamat M,
Kim B,
Mandoli A,
Marchini J,
Martens JHA,
Meacham S,
Megy K,
O'Connell J,
Petersen R,
Sharifi N,
Sheard SM,
Staley JR,
Tuna S,
van der Ent M,
Walter K,
Wang SY,
Wheeler E,
Wilder SP,
Iotchkova V,
Moore C,
Sambrook J,
Stunnenberg HG,
Di Angelantonio E,
Kaptoge S,
Kuijpers TW,
Carrillo-de-Santa-Pau E,
Juan D,
Rico D,
Valencia A,
Chen L,
Ge B,
Vasquez L,
Kwan T,
Garrido-Martín D,
Watt S,
Yang Y,
Guigo R,
Beck S,
Paul DS,
Pastinen T,
Bujold D,
Bourque G,
Frontini M,
Danesh J,
Roberts DJ,
Ouwehand WH,
Butterworth AS,
Soranzo N
Cell · 2016 · PMID 27863252 · open access
Questions about rs185120612
What is rs185120612?
rs185120612 is a single position in the genome, in or near the FNIP1 gene. Published research associates it with sum eosinophil basophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs185120612 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs185120612 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Sum eosinophil basophil counts (rs185120612). MyGeneLog™. https://www.mygenelog.com/variants/rs185120612
← See all variants