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Appendicular lean mass

near PPIAP76 · rs1850756

What the study found

Who was studied 181,862 European ancestry elderly individuals.

The effect Each copy of the C allele shifted the measure 0.0485 higher (95% confidence interval 0.034-0.063); p = 1 × 10−11.

How common The C allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 4, band 4q28.1 — between genes, 18.4 kb from PPIAP76.

What each result means

A/A No copy of the version the research linked to Appendicular lean mass. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Appendicular lean mass. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Appendicular lean mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1850756

What is rs1850756?

rs1850756 is a single position in the genome, in or near the near PPIAP76 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1850756 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1850756 come from?

GWAS Catalog, American journal of human genetics 2019, PMID:31761296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Appendicular lean mass (rs1850756). MyGeneLog™. https://www.mygenelog.com/variants/rs1850756

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