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F8W876 protein level (protein group normalized intensity)

MASP1 · rs184750711

What the study found

Who was studied 1,243 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.235 lower (95% confidence interval 0.16-0.31); p = 9 × 10−10.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 3, band 3q27.3 — in an intron of MASP1.

What each result means

C/C No copy of the version the research linked to F8W876 protein level (protein group normalized intensity). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to F8W876 protein level (protein group normalized intensity). That is a smaller link than two copies.
T/T Two copies of the version the research linked to F8W876 protein level (protein group normalized intensity). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs184750711

What is rs184750711?

rs184750711 is a single position in the genome, in or near the MASP1 gene. Published research associates it with f8w876 protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs184750711 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs184750711 come from?

GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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F8W876 protein level (protein group normalized intensity) (rs184750711). MyGeneLog™. https://www.mygenelog.com/variants/rs184750711

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