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Eye color

TYR · rs1847134

Where this position leads

Condition: Eye Color and Pigmentation

rs1847134 Condition: Eye Color and Pigmentation Eye Color and Pigmentation Condition rs1847134 rs1847134 TYR

What the study found

Who was studied 9,126 European ancestry individuals.

The effect Each copy of the A allele carried 1.58 times the odds of Eye color; p = 1 × 10−15.

How common The A allele had a frequency of about 68% in the people studied.

Where it sits Chromosome 11, band 11q14.3 — in an intron of TYR.

What each result means

A/A Two copies of the version the research linked to Eye color. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Eye color. That is a smaller link than two copies.
C/C No copy of the version the research linked to Eye color. This is the starting point the study compared everyone against.
Source
Web-based, participant-driven studies yield novel genetic associations for common traits
Eriksson N, Macpherson JM, Tung JY, Hon LS, Naughton B, Saxonov S, Avey L, Wojcicki A, Pe'er I, Mountain J
PLoS genetics · 2010 · PMID 20585627 · open access

Questions about rs1847134

What is rs1847134?

rs1847134 is a single position in the genome, in or near the TYR gene. Published research associates it with eye color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1847134 linked to?

On MyGeneLog this position is linked to Eye Color and Pigmentation. The research behind each link, and its sources, are set out on that condition page.

Does having rs1847134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1847134 come from?

GWAS Catalog, PLoS Genet 2010, PMID:20585627. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eye color (rs1847134). MyGeneLog™. https://www.mygenelog.com/variants/rs1847134

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