Sensitive

Peptic ulcer disease

CERKL · rs184426772

Where this position leads

Condition: Peptic Ulcer Disease

rs184426772 Condition: Peptic Ulcer Disease Peptic Ulcer Disease Condition rs184426772 rs184426772 CERKL

What the study found

Who was studied 29,739 Japanese ancestry cases, 240,675 Japanese ancestry controls.

The effect Each copy of the C allele shifted the measure 0.796 higher (95% confidence interval 0.52-1.07); p = 2 × 10−8.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 2, band 2q31.3 — in an intron of CERKL.

What each result means

C/C Two copies of the version the research linked to Peptic ulcer disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Peptic ulcer disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Peptic ulcer disease. This is the starting point the study compared everyone against.
Source

Questions about rs184426772

What is rs184426772?

rs184426772 is a single position in the genome, in or near the CERKL gene. Published research associates it with peptic ulcer disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs184426772 linked to?

On MyGeneLog this position is linked to Peptic Ulcer Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs184426772 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs184426772 come from?

GWAS Catalog, Nature genetics 2023, PMID:38036781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Peptic ulcer disease (rs184426772). MyGeneLog™. https://www.mygenelog.com/variants/rs184426772

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