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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 125,000 African ancestry individuals (MTAG boosted by total cholesterol and triglyceride samples).
The effect
Each copy of the G allele shifted the measure 0.216 lower (95% confidence interval 0.15-0.29); p = 1 × 10−9.
Where it sits Chromosome 19, band 19q13.43 — in the 5′ untranslated region of ZNF587B.
What each result means
A/ANo copy of the version the research linked to High-density lipoprotein levels (MTAG). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to High-density lipoprotein levels (MTAG). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to High-density lipoprotein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37669986 · open access
Questions about rs184238980
What is rs184238980?
rs184238980 is a single position in the genome, in or near the ZNF587B gene. Published research associates it with high-density lipoprotein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs184238980 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs184238980 come from?
GWAS Catalog, Nature communications 2023, PMID:37669986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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