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Who was studied 983 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.15 higher; p = 3 × 10−10.
How common The G allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 19, band 19q13.32 — in an intron of TOMM40.
What each result means
G/GTwo copies of the version the research linked to Cerebral amyloid deposition (PET imaging). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Cerebral amyloid deposition (PET imaging). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Cerebral amyloid deposition (PET imaging). This is the starting point the study compared everyone against.
Molecular psychiatry · 2021 · PMID 30361487 · open access
Questions about rs184017
What is rs184017?
rs184017 is a single position in the genome, in or near the TOMM40 gene. Published research associates it with cerebral amyloid deposition (pet imaging). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs184017 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE). The research behind each link, and its sources, are set out on that condition page.
Does having rs184017 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs184017 come from?
GWAS Catalog, Mol Psychiatry 2018, PMID:30361487. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 351312512218Reads by AI crawlersClaude1ChatGPT3Google · Gemini1Perplexity2Meta AI5Microsoft · Copilot0Amazon1Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total35Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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