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Secreting CD4 regulatory T cell %CD4 regulatory T cell

HNRNPLL · rs183949931

What the study found

Who was studied 3,437 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.567 lower (95% confidence interval 0.42-0.71); p = 6 × 10−14.

How common The C allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 2, band 2p22.1 — in an intron of HNRNPLL.

What each result means

C/C Two copies of the version the research linked to Secreting CD4 regulatory T cell %CD4 regulatory T cell. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Secreting CD4 regulatory T cell %CD4 regulatory T cell. That is a smaller link than two copies.
T/T No copy of the version the research linked to Secreting CD4 regulatory T cell %CD4 regulatory T cell. This is the starting point the study compared everyone against.
Source

Questions about rs183949931

What is rs183949931?

rs183949931 is a single position in the genome, in or near the HNRNPLL gene. Published research associates it with secreting cd4 regulatory t cell %cd4 regulatory t cell. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs183949931 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs183949931 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Secreting CD4 regulatory T cell %CD4 regulatory T cell (rs183949931). MyGeneLog™. https://www.mygenelog.com/variants/rs183949931

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