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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 162,774 Icelandic ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.42 lower (95% confidence interval 0.54-0.30); p = 4 × 10−11.
How common The G allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 6, band 6p22.3 — in an intron of GPLD1.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Serum alkaline phosphatase levels — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum alkaline phosphatase levels.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum alkaline phosphatase levels compared to the general population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020 · PMID 31666285
Questions about rs183821586
What is rs183821586?
rs183821586 is a single position in the genome, in or near the GPLD1 gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs183821586 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs183821586 come from?
GWAS Catalog, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020, PMID:31666285. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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