C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Asthma and hay fever compared to the general population. (GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24388013)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Asthma and hay fever. (GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24388013)
T/TPublished research associates this genotype with typical/baseline likelihood of Asthma and hay fever — no copies of the reported risk allele. (GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24388013)
rs1837253 is a single position in the genome, in or near the TSLP gene. Published research associates it with asthma and hay fever. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1837253 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs1837253 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1837253 come from?
GWAS Catalog, J Allergy Clin Immunol 2013, PMID:24388013. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.