Standard

Medication use (salicylic acid and derivatives)

CDKN2B-AS1 · rs1831733

Where this position leads

Condition: Medication Use as a Genetic Trait

rs1831733 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs1831733 rs1831733 CDKN2B-AS1

What the study found

Who was studied 61,583 European ancestry cases, 50,427 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0458 higher (95% confidence interval 0.03-0.061); p = 9 × 10−9.

How common The C allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 9, band 9p21.3 — in an intron of CDKN2B-AS1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (salicylic acid and derivatives) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (salicylic acid and derivatives).
T/T Published research associates this genotype with typical/baseline likelihood of Medication use (salicylic acid and derivatives) — no copies of the reported risk allele.
Source

Questions about rs1831733

What is rs1831733?

rs1831733 is a single position in the genome, in or near the CDKN2B-AS1 gene. Published research associates it with medication use (salicylic acid and derivatives). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1831733 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs1831733 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1831733 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (salicylic acid and derivatives) (rs1831733). MyGeneLog™. https://www.mygenelog.com/variants/rs1831733

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