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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 633 African American or Afro-Caribbean cases, 120,286 African American or Afro-Caribbean controls, 1,549 European ancestry cases, 446,736 European ancestry controls, 273 Hispanic or Latin American cases, 59,198 Hispanic or Latin American controls.
The effect
Each copy of the C allele shifted the measure 3.65 lower (95% confidence interval 3.63-3.67); p = 4 × 10−11.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 9, band 9p23 — in an intron of PTPRD.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Dyshidrosis (PheCode 705.1) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Dyshidrosis (PheCode 705.1).
T/TPublished research associates this genotype with typical/baseline likelihood of Dyshidrosis (PheCode 705.1) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs183168537
What is rs183168537?
rs183168537 is a single position in the genome, in or near the PTPRD gene. Published research associates it with dyshidrosis (phecode 705.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs183168537 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs183168537 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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