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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 98,735 African American or Afro-Caribbean individuals, 49,225 Hispanic or Latin American individuals, 5,475 East Asian ancestry individuals, 338,848 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0238 higher (95% confidence interval 0.017-0.031); p = 4 × 10−11.
How common The T allele had a frequency of about 29% in the people studied.
Where it sits Chromosome 9, band 9q31.2 — between genes, 24.7 kb from RNU6-1064P.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Hemoglobin A1c (HbA1c, mean, inv-norm transformed) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hemoglobin A1c (HbA1c, mean, inv-norm transformed).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hemoglobin A1c (HbA1c, mean, inv-norm transformed) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs1831382
What is rs1831382?
rs1831382 is a single position in the genome, in or near the near RNU6-1064P gene. Published research associates it with hemoglobin a1c (hba1c, mean, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1831382 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1831382 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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