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Proportion of activated microglia (inferior temporal cortex)

PKN2-AS1 · rs183093970

What the study found

Who was studied 219 individuals.

The effect Each copy of the G allele shifted the measure 0.153 higher; p = 5 × 10−10.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1p22.2 — in an intron of PKN2-AS1.

What each result means

A/A No copy of the version the research linked to Proportion of activated microglia (inferior temporal cortex). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Proportion of activated microglia (inferior temporal cortex). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Proportion of activated microglia (inferior temporal cortex). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs183093970

What is rs183093970?

rs183093970 is a single position in the genome, in or near the PKN2-AS1 gene. Published research associates it with proportion of activated microglia (inferior temporal cortex). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs183093970 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs183093970 come from?

GWAS Catalog, Nature communications 2019, PMID:30679421. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Proportion of activated microglia (inferior temporal cortex) (rs183093970). MyGeneLog™. https://www.mygenelog.com/variants/rs183093970

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