Sensitive

Neuroendocrine tumors (PheCode 209)

SGPL1 · rs183021871

Where this position leads

Condition: Neuroendocrine Tumors

rs183021871 Condition: Neuroendocrine Tumors Neuroendocrine Tumors Condition rs183021871 rs183021871 SGPL1

What the study found

Who was studied 211 African American or Afro-Caribbean cases, 121,601 African American or Afro-Caribbean controls, 540 European ancestry cases, 450,490 European ancestry controls.

The effect Each copy of the C allele shifted the measure 3.51 lower (95% confidence interval 3.49-3.53); p = 3 × 10−11.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 10, band 10q22.1 — inside SGPL1.

What each result means

C/C Two copies of the version the research linked to Neuroendocrine tumors (PheCode 209). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Neuroendocrine tumors (PheCode 209). That is a smaller link than two copies.
G/G No copy of the version the research linked to Neuroendocrine tumors (PheCode 209). This is the starting point the study compared everyone against.
Source

Questions about rs183021871

What is rs183021871?

rs183021871 is a single position in the genome, in or near the SGPL1 gene. Published research associates it with neuroendocrine tumors (phecode 209). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs183021871 linked to?

On MyGeneLog this position is linked to Neuroendocrine Tumors. The research behind each link, and its sources, are set out on that condition page.

Does having rs183021871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs183021871 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroendocrine tumors (PheCode 209) (rs183021871). MyGeneLog™. https://www.mygenelog.com/variants/rs183021871

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