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PDCD5 protein levels

TDRD12 · rs182893165

Where this position leads

Condition: Celiac Disease

rs182893165 Condition: Celiac Disease Celiac Disease Condition rs182893165 rs182893165 TDRD12

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.185 higher (95% confidence interval 0.13-0.24); p = 2 × 10−11.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 19, band 19q13.11 — in an intron of TDRD12.

What each result means

A/A Two copies of the version the research linked to PDCD5 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to PDCD5 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to PDCD5 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs182893165

What is rs182893165?

rs182893165 is a single position in the genome, in or near the TDRD12 gene. Published research associates it with pdcd5 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs182893165 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs182893165 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs182893165 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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PDCD5 protein levels (rs182893165). MyGeneLog™. https://www.mygenelog.com/variants/rs182893165

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