Sensitive

Alzheimer's disease

ZFYVE1 · rs182804071

Where this position leads

Condition: Alzheimer's Disease Risk (APOE)

rs182804071 Condition: Alzheimer's Disease Risk (APOE) Alzheimer's Disease Risk (APOE) Condition rs182804071 rs182804071 ZFYVE1

What the study found

Who was studied 2,559 Hispanic cases, 5,908 Hispanic controls.

The effect Each copy of the C allele carried 9.67 times the odds of Alzheimer's disease (95% confidence interval 4.71-19.88); p = 7 × 10−10.

How common The C allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 14, band 14q24.2 — in an intron of ZFYVE1.

What each result means

C/C Two copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
Source

Questions about rs182804071

What is rs182804071?

rs182804071 is a single position in the genome, in or near the ZFYVE1 gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs182804071 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE). The research behind each link, and its sources, are set out on that condition page.

Does having rs182804071 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs182804071 come from?

GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2026, PMID:41755704. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease (rs182804071). MyGeneLog™. https://www.mygenelog.com/variants/rs182804071

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