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Hypothyroidism

near BRD7 · rs182787262

Where this position leads

Condition: Hypothyroidism

rs182787262 Condition: Hypothyroidism Hypothyroidism Condition rs182787262 rs182787262 near BRD7

What the study found

Who was studied 58,783 European ancestry cases, 633,203 European ancestry controls.

The effect Each copy of the C allele carried 1.45 times the odds of Hypothyroidism (95% confidence interval 1.33-1.58); p = 1 × 10−16.

Where it sits Chromosome 16, band 16q12.1 — between genes, 8.9 kb from BRD7.

What each result means

C/C Two copies of the version the research linked to Hypothyroidism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hypothyroidism. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hypothyroidism. This is the starting point the study compared everyone against.
Source

Questions about rs182787262

What is rs182787262?

rs182787262 is a single position in the genome, in or near the near BRD7 gene. Published research associates it with hypothyroidism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs182787262 linked to?

On MyGeneLog this position is linked to Hypothyroidism. The research behind each link, and its sources, are set out on that condition page.

Does having rs182787262 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs182787262 come from?

GWAS Catalog, European journal of endocrinology 2024, PMID:39067062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypothyroidism (rs182787262). MyGeneLog™. https://www.mygenelog.com/variants/rs182787262

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