Personal history of allergy to medicinal agents (PheCode 977)
near LINC01222 · rs182500148
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Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 304 African American or Afro-Caribbean cases, 120,775 African American or Afro-Caribbean controls, 535 European ancestry cases, 448,351 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 3.5 lower (95% confidence interval 3.48-3.52); p = 4 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — between genes, 21.5 kb from LINC01222.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Personal history of allergy to medicinal agents (PheCode 977) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Personal history of allergy to medicinal agents (PheCode 977).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Personal history of allergy to medicinal agents (PheCode 977) compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs182500148
What is rs182500148?
rs182500148 is a single position in the genome, in or near the near LINC01222 gene. Published research associates it with personal history of allergy to medicinal agents (phecode 977). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs182500148 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs182500148 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Personal history of allergy to medicinal agents (PheCode 977) (rs182500148). MyGeneLog™. https://www.mygenelog.com/variants/rs182500148