Sensitive

Cancer code, self-reported: breast cancer (UKB data field 20001_1002)

near MRPS30 · rs182431363

Where this position leads

Condition: Breast Cancer

rs182431363 Condition: Breast Cancer Breast Cancer Condition rs182431363 rs182431363 near MRPS30

What the study found

Who was studied 10,152 European ancestry cases, 446,124 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.9 higher (95% confidence interval 0.62-1.18); p = 4 × 10−10.

How common The C allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 5, band 5p12 — between genes, 97 kb from MRPS30.

What each result means

C/C Two copies of the version the research linked to Cancer code, self-reported: breast cancer (UKB data field 20001_1002). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cancer code, self-reported: breast cancer (UKB data field 20001_1002). That is a smaller link than two copies.
T/T No copy of the version the research linked to Cancer code, self-reported: breast cancer (UKB data field 20001_1002). This is the starting point the study compared everyone against.
Source

Questions about rs182431363

What is rs182431363?

rs182431363 is a single position in the genome, in or near the near MRPS30 gene. Published research associates it with cancer code, self-reported: breast cancer (ukb data field 20001_1002). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs182431363 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs182431363 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs182431363 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cancer code, self-reported: breast cancer (UKB data field 20001_1002) (rs182431363). MyGeneLog™. https://www.mygenelog.com/variants/rs182431363

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